| Author: | Lo, Shun-lap Sunny |
| Title: | A study of the effect of low frequency low intensity pulsed magnetotherapy on the blood flow and oxygen perfusion of ischaemic feet of diabetic patients |
| Degree: | M.Sc. |
| Year: | 1998 |
| Subject: | Magnetotherapy Foot -- Diseases -- Treatment Diabetes -- Complications Hong Kong Polytechnic University -- Dissertations |
| Department: | Multi-disciplinary Studies Department of Rehabilitation Sciences |
| Pages: | x, 70 leaves : ill. (some col.) ; 30 cm |
| Language: | English |
| Abstract: | Changes in foot oxygenation and peripheral blood flow were examined in 26 Type II diabetic patients (NIDDM) with foot ischaemia (ankle-brachial index < 0.85) under active or sham magnetotherapy. Magnetotherapy is postulated to help in peripheral circulation but without raising local interstitial temperature. This would minimize risk of burn to those having thermal insensitivity. Improvement in local circulation implies less ischaemic pain, enhanced healing rate and better arrest of ischaemic syndromes. A randomized two groups repeated measures design was used. Patients were selected in a regional acute hospital between June,1997 to January, 1998. Fourteen of them were recruited in the experimental group and the rest of them in the sham group. The present study used 12Hz, 5 x 10-4 Tesla alternating field for magnetotherapy stimulation (Magnetopulse, Australia). Peripheral blood flow (PBF) of the feet was measured by a 8MHz Doppler ultrasound probe (HNE Diagnostics) stabilized by a gadget over the dorsalis pedis artery. Skin microcirculation was measured by a Clarke-type transcutaneous oxygen (TcPO2) monitor (Roche Bioelectronics) positioned at the dorsum of the foot. Readings were taken from fifteen minutes before commencement of active or sham intervention for ascertaining baseline values. PBF and TcPO2 were taken at five-minute intervals during the data collection period. Thirty minutes of active or sham intervention was administered. At the end of twenty minutes, measurements were recorded to evaluate the after-effects. Demographic variables and baseline measurements of PBF and TcPO2 were not statistically different among active and sham groups. Both parameters rose significantly after active intervention was administered reaching a "peak" value at the thirtieth minute. No ascending pattern was seen in both control groups. Simultaneous decreasing trends were also seen in both parameters after active intervention was stopped. All ascending and descending trends in the active intervention group regressed linearly with time. Parameters in the sham group were not regressing well. Skin oxygen tension and peripheral blood flow rose about 38.5% and 97% respectively to the peak and eventually increased by 19.5% and 44% respectively by the end of data collection. Repeated measures ANOVA tests were performed as assumptions were met. Comparing initial, peak and end of intervention of TcPO2 in the active intervention group revealed significant differences with F Value=27.33, p=0.000. Eor blood flow data, the F value = 73.76, p=0.000 which also revealed significant differences between the three timeslots. This study showed that the selected dosage of magnetotherapy could improve local peripheral circulation in diabetic patients with ischaemic feet and peak values were obtained at 30 minutes after commencement of intervention. Further studies could enhance power of the study by increasing the sample size. Therapeutic effects such as reducing ischaemic pain and improvement in healing diabetic ulceration warrant further studies. |
| Rights: | All rights reserved |
| Access: | restricted access |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| b14535981.pdf | For All Users (off-campus access for PolyU Staff & Students only) | 5.14 MB | Adobe PDF | View/Open |
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