A randomized controlled trial for maintaining peripheral intravenous lock in children

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A randomized controlled trial for maintaining peripheral intravenous lock in children

 

Author: Kwong, Kam-yuk Tany
Title: A randomized controlled trial for maintaining peripheral intravenous lock in children
Degree: M.Sc.
Year: 2003
Subject: Hong Kong Polytechnic University -- Dissertations
Injections, Intravenous
Intravenous catheterization
Children -- Hospital care -- Evaluation
Department: School of Nursing
Pages: iv, 103, 12 leaves : ill. (some col.) ; 30 cm
Language: English
InnoPac Record: http://library.polyu.edu.hk/record=b1686671
URI: http://theses.lib.polyu.edu.hk/handle/200/2723
Abstract: The objectives of this study are to evaluate the effectiveness of three flush solutions:normal saline, 1 unit/ml heparin saline and 10units/ml heparin saline for maintaining peripheral intravenous locks in children, and to establish research-based practice in the study hospital. The design was a prospective, randomized controlled, double blind study. Forty-one subjects randomized into 1unit/ml heparin saline group, the conventional practice in the study hospital (control group), and forty-one subjects into normal saline and 10units/ml heparin saline groups (experimental groups). The setting was a 34-bed general pediatric and adolescent medicine ward in an acute care hospital in Hong Kong. One hundred and twenty three subjects with 123 intravenous locks were recruited over nine months. The main outcome measures were the IV catheter longevity: the time from first flush to catheter removal and the incidence of IV complications: redness, swelling, resistance to flush, and leaking at IV site. The study found no statistically significant difference in the mean catheter longevity, estimated survival and the incidence of IV complications between the three groups. The estimated survival of 1 unit/ml heparin saline group has a trend of better survival between the three groups. In uncensored observations, the mean catheter longevity of 1unit/ml heparin saline group (49.8 hours) was 17 hours longer than normal saline group (32.5 hours). The conclusions of this study were that 1unit/ml heparin saline (current practice) and 10units/ml heparin saline had no benefit over saline as well as 10unit/ml heparin saline flush. The change of practice to saline was justified. The annual cost saving in the pediatric unit of the study hospital was $100,513 and 420 nursing hours.

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