Dosimetric effect of belly board position on small bowel and bladder volume irradiated for postoperative 3-dimensional conformal radiotherapy of rectal cancer

Pao Yue-kong Library Electronic Theses Database

Dosimetric effect of belly board position on small bowel and bladder volume irradiated for postoperative 3-dimensional conformal radiotherapy of rectal cancer

 

Author: Hung, Wai-king
Title: Dosimetric effect of belly board position on small bowel and bladder volume irradiated for postoperative 3-dimensional conformal radiotherapy of rectal cancer
Degree: M.Sc.
Year: 2009
Subject: Hong Kong Polytechnic University -- Dissertations.
Rectum -- Cancer -- Radiotherapy.
Rectum -- Cancer -- Treatment.
Radiation dosimetry.
Department: Dept. of Health Technology and Informatics
Pages: viii, 73 leaves : ill. (some col.) ; 30 cm.
Language: English
InnoPac Record: http://library.polyu.edu.hk/record=b2305537
URI: http://theses.lib.polyu.edu.hk/handle/200/4035
Abstract: Purpose/objectives: To evaluate the effect of belly board position on dose to the small bowel and bladder in rectal cancer patients receiving 3DCRT. Materials/Methods: Fourteen rectal cancer patients planned to receive 3DCRT were included. With full bladder, three sets of CT scans were performed with the patients positioned at three different levels against the lower border of the aperture of the belly board: Position 1 (PI), at the interspace of L5/SI; Position 2 (P2), at the lower end of the sacroiliac joint; Position 3 (P3), at the upper end of the symphysis pubis. Three-dimensional conformal plans were generated on each of the CT set. The dose given was 40 Gy followed by a 10 Gy boost in 25 fractions. The dose distribution to the small bowel and bladder was evaluated by the dose-volume histogram from 5 to 50 Gy in 5 Gy steps and analyzed using one-way repeated measures of ANOVA. Regression analysis was used to evaluate the relationship between bladder and small bowel changes. Results: The volume of small bowel irradiated at 5-10 Gy increased in the order of PI, P2, and P3 with an average of 126.8+-4.95 (S.D.) cm3, 145.6+-1.25 (S.D.) cm3, 221.05+-27 (S.D.) cm3 respectively and tested to be significantly different (p<0.05). However from 15 Gy - 20 Gy, the volume of irradiated small bowel was much reduced with an average of 83.05 cm3 at PI, 66.95 cm3 at P2 and 73 cm3 at P3 with significant difference between PI and P2 (p<0.05). At >25 Gy, very little difference was found among the three positions. For the bladder, the volume irradiated was expressed as the percentage volume of the whole bladder. Between 5-10 Gy, over 98% of the bladder volume was included. Above 10 Gy, the percentage volume of the bladder irradiated was about the same at PI and P2 but significantly lower at P3 at 15 Gy with a difference of 18.6% (p<0.02). The bladder volume was the largest at P3 for all cases in the CT slices. The CT scans were performed in the order of PI, P2 and P3 with P3 being the last so the bladder was the most filled by the time the P3 position was scanned. Regression analysis revealed a negative correlation between the bladder volume and the small bowel volume. Conclusions: Total volume of small bowel irradiated was the lowest at PI. Bladder sparing was the best at P3 as there was more space at the anterior abdomen wall for the fall down of bladder. The increase in bladder volume has a displacement effect on the volume of irradiated small bowel. The optimum position for using the belly board for small bowel sparing would be at PI with a more distended bladder.

Files in this item

Files Size Format
b23055376.pdf 1.997Mb PDF
Copyright Undertaking
As a bona fide Library user, I declare that:
  1. I will abide by the rules and legal ordinances governing copyright regarding the use of the Database.
  2. I will use the Database for the purpose of my research or private study only and not for circulation or further reproduction or any other purpose.
  3. I agree to indemnify and hold the University harmless from and against any loss, damage, cost, liability or expenses arising from copyright infringement or unauthorized usage.
By downloading any item(s) listed above, you acknowledge that you have read and understood the copyright undertaking as stated above, and agree to be bound by all of its terms.

     

Quick Search

Browse

More Information