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dc.contributorMulti-disciplinary Studiesen_US
dc.contributorDepartment of Rehabilitation Sciencesen_US
dc.creatorLaw, Pui-wah Pearl-
dc.identifier.urihttps://theses.lib.polyu.edu.hk/handle/200/4289-
dc.languageEnglishen_US
dc.publisherHong Kong Polytechnic University-
dc.rightsAll rights reserveden_US
dc.titleThe optimal stimulation frequency of transcutaneous electrical nerve stimulation (TENS) on people with knee osteoarthritisen_US
dcterms.abstractTENS is an effective means of alleviating pain. In past decades it has been widely used by physiotherapists in managing various pain conditions, including osteoarthritic (OA) knee. Clinical studies have indicated that TENS of different frequencies may work through different endogenous opioid system for pain relief Low frequency (2-4 hertz) TENS triggers the release of enkephalin and |B-endorphin acting on the mu and delta receptors, whereas high frequency (100 Hz) TENS appears to involve mostly dynorphin and acts on the kappa opioid receptors. Studies in rats have suggested that the use of alternating low frequency TENS with high frequency would produce a more potent anti-nociceptive effect. The present study was designed to compare the analgesic effect of this alternating frequency mode of treatment to a fixed high or low frequency stimulation in the treatment of patients with OA knees. Patients suffering from forty-eight painful OA knees were randomly divided into four groups receiving TENS at pulse width of 200us to 600us for 40 minutes for either (I) 2 Hz., (II) 100Hz, (111) 2/100 Hz, or (IV) placebo TENS. Treatment was administered 5 days a week for 2 weeks. A follow-up session was conducted 2 weeks after the treatment period. Outcome measures (I) The visual analogue scale was used to measure the intensity of pain of the patients. (II) The "timed up-and-go" test was used to assess patient's functional mobility. (III) Range of knee motion including both pain limit range and maximum passive range was measured. Repeated measures ANOVA was used to compare the pre- and post-treatment data across sessions and between groups. Results: All of the 3 active TENS groups (2Hz, 100Hz, 2/100Hz) demonstrated a significant reduction in OA knee pain whereas the placebo group did not. In the first session, TENS at 100 Hz produced a significantly greater analgesic effect than TENS at 2Hz and placebo at 60 min after treatment (p=0.047, p=0.028 respectively). However, no significant between-group difference was noted among the TENS2/100 group and the other two active TENS groups in all treatment sessions. Conclusion: Our findings demonstrated that 2 weeks of repeated applications of TENS at 2 Hz, 100 Hz or 2/100 Hz significantly reduced OA knee pain, whereas the placebo group did not.en_US
dcterms.extentix, 98 leaves : ill. (some col.) ; 30 cmen_US
dcterms.isPartOfPolyU Electronic Thesesen_US
dcterms.issued2002en_US
dcterms.educationalLevelAll Masteren_US
dcterms.educationalLevelM.Sc.en_US
dcterms.LCSHHong Kong Polytechnic University -- Dissertationsen_US
dcterms.LCSHTranscutaneous electrical nerve stimulationen_US
dcterms.LCSHOsteoarthritis -- Treatmenten_US
dcterms.LCSHKnee -- Diseases -- Treatmenten_US
dcterms.accessRightsrestricted accessen_US

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Please use this identifier to cite or link to this item: https://theses.lib.polyu.edu.hk/handle/200/4289