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dc.contributorDepartment of Electronic and Information Engineeringen_US
dc.contributor.advisorLeung, H. F. Frank (EIE)en_US
dc.contributor.advisorZheng, Yong-ping (BME)en_US
dc.creatorHuang, Zixun-
dc.identifier.urihttps://theses.lib.polyu.edu.hk/handle/200/12489-
dc.languageEnglishen_US
dc.publisherHong Kong Polytechnic Universityen_US
dc.rightsAll rights reserveden_US
dc.titleDeep learning for scoliosis assessmenten_US
dcterms.abstractScoliosis is a medical condition in which the spine has a sideways deformity larger than 10 degrees. It occurs in 2-4% of teenagers. 3D ultrasound imaging shows great promise for scoliosis diagnosis thanks to its low-cost, radiation-free, and real-time characteristics. In clinical scoliosis diagnosis, experts need to segment all the spinal features for scoliosis assessment, which is a tedious and time-consuming job. Benefiting from the powerful feature extraction capability, deep learning-based algorithms have been widely used in computer vision recently. These algorithms make it possible to extract spinal bone features from images automatically. In this thesis, we performed an in-depth study on deep-learning-based spine segmentation via ultrasound imaging, and proposed robust and effective learning algorithms to facilitate ultrasound spine segmentation.en_US
dcterms.abstractDifferent from natural images, ultrasound images have low quality and tend to contain scan noise. General deep learning-based algorithms cannot capture bone features robustly. Considering that the pixel values in the noisy regions are changing frequently, we proposed total variance loss to reduce the sensitivity of the network to the image regions with high-frequency energy, which improves the robustness of the segmentation model to scan noise.en_US
dcterms.abstractNext, we analyze different spinal bone features in the ultrasound images, which contain strong structural relationships among each other. We revisit the self-attention mechanism in representation learning and propose to introduce the structural knowledge into the key representation in self-attention. By this means, the network explores contextual and structural information in the learned spine features, improving the segmentation accuracy as a result.en_US
dcterms.abstractBesides improving the robustness of the segmentation model by considering the loss function, we propose a weakly-supervised framework to remove scan noise from unpaired samples. A dual adversarial learning strategy is used to handle the problem of data imbalance. Moreover, we present a novel multi-task framework to achieve high inference efficiency. To establish the interaction between the noise removal and spine segmentation tasks, we propose a selective feature-sharing strategy to transfer only beneficial features.en_US
dcterms.abstractFinally, owing to the lack of information, such as the bone index and spine vertebrae landmark coordinates, a semantic segmentation algorithm might be difficult to measure the scoliosis degree automatically. To achieve a fully automatic measurement of scoliosis, we proposed a landmarks localization algorithm to estimate the spine vertebrae coordinates directly. As we usually have strong prior knowledge of the distribution of landmarks in medical images, we proposed a novel and effective landmark localization approach with landmark distribution prior. It leverages normalizing flows for the underlying landmark distribution estimation and utilizes the learned distribution prior to penalizing the landmark localization.en_US
dcterms.abstractThe spinal segmentation frameworks proposed in this thesis are evaluated through comparisons with other state-of-the-art methods on our in-house spinal ultrasound dataset. On the other hand, owing to the lack of landmarks annotation in our dataset, we evaluate our proposed landmark localization on three publicly available datasets of X-ray images. Experimental results show that our proposed algorithms achieve encouraging performance. Ablation studies demonstrate that the proposed designs can facilitate the learning of spinal segmentation and landmark localization.en_US
dcterms.extent150 pages : color illustrationsen_US
dcterms.isPartOfPolyU Electronic Thesesen_US
dcterms.issued2023en_US
dcterms.educationalLevelPh.D.en_US
dcterms.educationalLevelAll Doctorateen_US
dcterms.LCSHScoliosis -- Diagnosisen_US
dcterms.LCSHSpine -- Abnormalities -- Diagnosisen_US
dcterms.LCSHMachine learningen_US
dcterms.LCSHHong Kong Polytechnic University -- Dissertationsen_US
dcterms.accessRightsopen accessen_US

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Please use this identifier to cite or link to this item: https://theses.lib.polyu.edu.hk/handle/200/12489