| Author: | Wang, Qingzhuo |
| Title: | Preparation of exosome/quantum dots-based drug nanocarriers |
| Advisors: | Cheung, Chung Wai James (BME) |
| Degree: | M.Sc. |
| Year: | 2024 |
| Subject: | Drug carriers (Pharmacy) Drug delivery systems Cell organelles Nanomedicine Hong Kong Polytechnic University -- Dissertations |
| Department: | Department of Biomedical Engineering |
| Pages: | 1 volume (unpaged) : color illustrations |
| Language: | English |
| Abstract: | Exosomes are naturally occurring extracellular vesicles and are considered to be associated with exchanging molecules between cells. As a viable platform for nano drug delivery like cancer therapeutics, exosomes can be well designed to specifically target cancer cells, reducing toxicity to normal cells as well as improving the efficacy of cancer treatments due to the theoretical advantages of high biocompatibility, prolonged retention time which may be potentially superior to traditional synthetic drug carriers. The nanocarriers modified with Ag2S QDs emitting in the NIR-II wavelength range allow for deeper tissue penetration and enable non-invasive monitoring of drug release. In the experiment, the formation of a novel exosomal drug delivery system labeled with Ag2S QDs is intended and it is expected to realize a targeted drug release system with real-time tracking in the NIR-II window in the future. |
| Rights: | All rights reserved |
| Access: | restricted access |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 7421.pdf | For All Users (off-campus access for PolyU Staff & Students only) | 1.16 MB | Adobe PDF | View/Open |
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