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dc.contributorDepartment of Rehabilitation Sciencesen_US
dc.contributor.advisorNg, Shamay (RS)en_US
dc.creatorPan, Hong-
dc.identifier.urihttps://theses.lib.polyu.edu.hk/handle/200/13922-
dc.languageEnglishen_US
dc.publisherHong Kong Polytechnic Universityen_US
dc.rightsAll rights reserveden_US
dc.titleMirror therapy combined with bilateral transcutaneous electrical nerve stimulation improves upper extremity motor recovery in people with stroke : randomized controlled trialsen_US
dcterms.abstractPrevious evidence showed that mirror therapy (MT) alone or bilateral transcutaneous electrical nerve stimulation (Bi-TENS) alone is an effective treatment for improving the paretic side recovery of upper extremity motor function in people with stroke. Given the advantage of MT can recruit additional neural pathway to elicit cortical activation, it is reasonable to hypothesize that MT combined with Bi-TENS can exert synergistic effects to improve the recovery of upper extremity motor function in people with stroke.en_US
dcterms.abstractThis thesis begins with study 1 of systematic review and meta-analysis. The positive findings suggest that MT combined with electrical stimulation may be effective in improving upper extremity motor function in people with stroke, especially for sub-acute stroke (SMD 0.56, 95% CI 0.1-1.01, P = 0.02, I2 = 63%).en_US
dcterms.abstractIn study 2, we investigated the abilities of paretic grip strength, Fugl-Meyer Assessment-Upper Extremity (FMA-UE), Wolf Motor Function Test (WMFT), and Upper Extremity Functional Index (UEFI) to predict the Stroke Impact Scale (SIS) in people with chronic stroke. We identified the UEFI as the most potent predictor for SIS in people with stroke (β = 0.487).en_US
dcterms.abstractIn study 3, we conducted one cross-sectional study to identify reliable and valid outcome measures for the main study. We then examined the psychometric properties of two potentials assessment tools. Both UEFI (intraclass correlation coefficient [ICC]3,1 = 0.87) and SATIS-Stroke (ICC3,1 = 0.91) were proved to be reliable and valid for the assessments of upper extremity motor function in daily life living and the satisfaction with social participation, respectively, in people with stroke.en_US
dcterms.abstractIn study 4 and 5, our main study, we examined whether the combination of MT + Bi-TENS would be more effective than the combination of Sham-MT + Bi-TENS for improving upper extremity impairment, motor function, and health-related outcome measures in people with sub-acute and chronic stroke, respectively.en_US
dcterms.abstractOur findings reveal that MT + Bi-TENS + conventional therapy group showed significantly greater improvement in FMA-UE scores at A1 (Mean Difference (MD) = 5.7, P < 0.001) and A2 (MD = 11.8, P < 0.001), maximum paretic grip strength at A1 (MD = 2.9, P < 0.001) and A2 (MD = 4.6, P < 0.001), and C-CIM scores at A2 (MD = 3.9, P = 0.002) in 30 people with sub-acute stroke compared with Sham-MT + Bi-TENS + conventional therapy in people with sub-acute stroke.en_US
dcterms.abstractMT + Bi-TENS group showed significantly improvement in FMA-UE (Mean Difference (MD) = 5.2, P < 0.001) and WMFT (MD = 3.7, P = 0.001) scores at A2 compared with Sham-MT + Bi-TENS in 60 people with chronic stroke.en_US
dcterms.extentxxvii, 459 pages : color illustrationsen_US
dcterms.isPartOfPolyU Electronic Thesesen_US
dcterms.issued2025en_US
dcterms.educationalLevelPh.D.en_US
dcterms.educationalLevelAll Doctorateen_US
dcterms.accessRightsopen accessen_US

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Please use this identifier to cite or link to this item: https://theses.lib.polyu.edu.hk/handle/200/13922