| Author: | Lu, Hongjian |
| Title: | Central venous pressure measurement system based on fiber-optic Fabry-Pérot sensor |
| Advisors: | Yu, Changyuan (EEE) |
| Degree: | M.Sc. |
| Year: | 2025 |
| Department: | Department of Electrical and Electronic Engineering |
| Pages: | vii, 54 pages : color illustrations |
| Language: | English |
| Abstract: | Accurate and continuous monitoring of central venous pressure (CVP) plays a crucial role in assessing cardiac preload and guiding fluid therapy in intensive care. Conventional electronic pressure transducers, although widely used, suffer from limitations such as susceptibility to electromagnetic interference, baseline drift, and size constraints, which hinder their long-term deployment in clinical environments. This study proposes and validates a fiber-optic Fabry-Pérot (FP) interferometric pressure sensing system for real-time CVP monitoring. The system was designed with both single-mode and multi-mode fiber configurations and utilized intensity-based and white-light interferometry for signal demodulation. A series of in vitro and in vivo experiments were conducted to evaluate sensor performance. In vivo validation was performed on a swine model with sensor insertion via a central venous catheter. The results showed that the system could successfully capture key waveform components such as a, c, and v waves, demonstrating excellent frequency response and temporal resolution. Positional changes in the animal model further validated the sensor’s responsiveness to physiological pressure variations. Compared to a standard medical monitor, the fiber-optic system achieved reliable tracking of dynamic pressure trends with a deviation of less than ±2.5 mmHg. These findings suggest that the proposed fiber-optic FP sensor provides a viable, stable, and miniaturized solution for long-term CVP monitoring. It shows strong potential for application in intensive care settings where continuous and interference-free measurements are essential. |
| Rights: | All rights reserved |
| Access: | restricted access |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 8721.pdf | For All Users (off-campus access for PolyU Staff & Students only) | 1.57 MB | Adobe PDF | View/Open |
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