Author: Poh, Kwun-yin
Title: To assess whether the Greulich-Pyle method of bone age assessment is applicable to the Hong Kong Chinese children
Degree: M.Sc.
Year: 2000
Subject: Skeletal maturity -- China -- Hong Kong
Children -- China -- Hong Kong
Chinese -- China -- Hong Kong
Hong Kong Polytechnic University -- Dissertations
Department: Multi-disciplinary Studies
Department of Optometry and Radiography
Pages: 75, [19] leaves : ill. ; 30 cm
Language: English
Abstract: This study assessed the applicability of bone age determination in Hong Kong Chinese children using the Greulich-Pyle method and investigated the influences of readers' experience on the measured bone ages. Plain hand radiographs of 719 children (neonatal to 18.9 years) attended the Accident & Emergency Department of the Pamela Youde Nethersole Eastern Hospital between January 1994 and December 1999 were analyzed by three radiologists of various film-reading experiences. The readers were blinded to the age of the children. 46 images were reassessed by the same two readers (Reader 2 and Reader 3) one-month later. The mean intraobserver variation was lower for the experienced reader but was not statistically significant at the 5% level (p=0.87 for Reader 2 and 0.42 for Reader 3 respectively). The interobserver variation between Reader 2 and Reader 3 was not statistically significant (Sig.=0.059). The differences between the assigned bone age and the chronological age in early, middle, late childhood and adolescence were - 0.07 +- 0.46, -0.73 +- 0.90, -0.27 +- 1.18 and 0.33 +- 1.05 respectively for boys and -0.11 +- 0.51, -0.45 +- 1.03, 0.02 +- 0.99 and 0.18 +- 0.88 respectively for girls. The differences were statistically significant in middle, late childhood and adolescence (p=<.0005, 0.032 and <.0005) for boys and in early and middle childhood (p=0.042 and 0.003) for girls. Measurements underestimated the chronological age significantly in middle and late childhood of boys and early and middle childhood of girls, while the assigned bone age was significantly more advanced in adolescence of boys. Our data dismiss the hypothesis that there is no difference between the chronological age and the assigned bone age using the Greulich-Pyle method. We suggest that a local calibration of the Greulich-Pyle atlas or a switch to another bone age method is necessary for effective timing of clinical interventions.
Rights: All rights reserved
Access: restricted access

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