|Author:||Chan, Chui Sim|
|Title:||The use of JUC physical antimicrobial spray dressing in managing radiation-induced acute skin reaction, pain and pruritus in cancer patient receiving radiation therapy|
|Subject:||Cancer -- Radiotherapy -- Complications -- Treatment.|
Hong Kong Polytechnic University -- Dissertations
|Department:||School of Nursing|
|Pages:||xvii, 150 leaves : col. ill. ; 30 cm.|
|Abstract:||Aim: This study aims to examine the effect of using JUC Physical Antimicrobial Spray Dressing in managing radiation-induced acute skin reaction, pain and pruritus in cancer patient receiving radiation therapy. Design: It was a prospective, single-blinded, randomized control trial which was conducted in an oncology unit of an acute public hospital in Hong Kong. Thirty head and neck or breast cancer subjects were randomly assigned to control or experimental groups. Control group subjects were instructed to apply aqueous cream topically to irradiated skin twice per day starting from their first day of radiation treatment till two weeks after treatment completion. Experimental subjects used JUC spray dressing and aqueous cream instead. Severity of radiation-induced skin reaction (CTCAE v.3) of the subjects, and pain and pruritus scores were assessed before commencing the radiation treatment and weekly during study period. The onset of developing skin wound and time period for wound healing was recorded. The sizes of the skin wounds were measured weekly. Bacterial cultures over irradiated skin were collected before, in the middle, and at the end of the radiation treatment. Results: Statistically difference was found in bacterial cultures over irradiated sites (p=0.046) but no statistically significant difference was found between control and experimental groups in the other outcome measures. There was a trend that the use of JUC spray dressing could delay the onset of wound development, shorten the wound healing time, and reduce the wound sizes. A trend of delaying the onset of grade 3 skin reaction and decreasing the severity of skin reaction was also noted in this study. Conclusion: The addition of JUC spray dressing might have effects on decreasing the severity of radiation-induced skin reaction, delaying the onset of wound development, fastening the wound healing process, and reducing the wound sizes. Identified areas are suggested for future studies to confirm the effectiveness of JUC spray dressing.|
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