Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor | Faculty of Health and Social Sciences | en_US |
dc.contributor.advisor | Tsang, William (FHSS) | - |
dc.contributor.advisor | Chow, Daniel (FHSS) | - |
dc.creator | Lui, Ming Fung Godfrey | - |
dc.identifier.uri | https://theses.lib.polyu.edu.hk/handle/200/8938 | - |
dc.language | English | en_US |
dc.publisher | Hong Kong Polytechnic University | - |
dc.rights | All rights reserved | en_US |
dc.title | Randomized controlled trial of the single-dose effect of melatonin on postural control and concurrent cognitive performance | en_US |
dcterms.abstract | Introduction: The release of endogenous melatonin declines with age. However, melatonin is an easily accessible dietary supplement for older adults with sleeping difficulties. Dual-tasking is a common daily activity that often requires extra attentional resources, especially in older adults. Falling downstairs is a leading cause of accidental death. Studies of the effect of melatonin on postural control after stepping down while performing a concurrent auditory response task are limited; therefore, this study was performed to investigate postural control after stepping down while dual-tasking with or without the administration of melatonin. Method: A randomized, double-blind, placebo-controlled, cross-over study was conducted in 34 older adults, who performed (1) an auditory Stroop test, (2) a stepping-down task, (3) a stepping-down task with a concurrent auditory response, and (4) a 30-second double-leg stance on a foam rubber mat with the eyes open, both before and 1 hour after taking either melatonin or a placebo (randomly assigned). A 7-day washout period was provided between assessment occasions. A two-way repeated-measures analysis of variance was conducted to analyze the interactive effects of treatment and time. Results: A statistically significant difference was found in the sway area before and 1 hour after melatonin administration while dual-tasking and in the 30-second double-leg stance with eyes open. However, no statistically significant difference was seen in cognitive task performance. Discussion and Conclusions: Melatonin decreases postural control in older adults when dual-tasking and when performing a 30-second double-leg stance with eyes open. Because melatonin is easily accessible, safety precautions should be taken with those who have a risk of postural imbalance and are prone to falls. | en_US |
dcterms.extent | xiii, 121 pages : color illustrations | en_US |
dcterms.isPartOf | PolyU Electronic Theses | en_US |
dcterms.issued | 2016 | en_US |
dcterms.educationalLevel | All Doctorate | en_US |
dcterms.educationalLevel | DHSc | en_US |
dcterms.LCSH | Melatonin -- Physiological effect. | en_US |
dcterms.LCSH | Melatonin -- Therapeutic use. | en_US |
dcterms.LCSH | Hong Kong Polytechnic University -- Dissertations | en_US |
dcterms.accessRights | restricted access | en_US |
Files in This Item:
File | Description | Size | Format | |
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b29616992.pdf | For All Users (off-campus access for PolyU Staff & Students only) | 3.28 MB | Adobe PDF | View/Open |
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