Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor | Department of Applied Biology and Chemical Technology | en_US |
| dc.creator | Lai, Ying Han | - |
| dc.identifier.uri | https://theses.lib.polyu.edu.hk/handle/200/6977 | - |
| dc.language | English | en_US |
| dc.publisher | Hong Kong Polytechnic University | - |
| dc.rights | All rights reserved | en_US |
| dc.title | Rapid differentiation of herbal medicines by matrix-assisted laser desorption/ionization mass spectrometry | en_US |
| dcterms.abstract | A matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS)-based approach has been developed and demonstrated for rapid differentiation of herbal medicines in this study. This approach typically involved a brief extraction to a small amount of herbal powder followed by MALDI-MS analysis. The MALDI-MS spectra obtained were characteristic of the herbal species and thus could act as the fingerprints of the species. This approach was used to differentiate between Panax ginseng (Asian ginseng) and Panax quinquefolius (American ginseng), between Schisandrae sphenanthera (southern magnoliavine fruit, Nan-Wuweizi) and Schisandrae chinensis (northern magnoliavine fruit, Bei-Wuweizi), and among Angelica sinensis (Chinese Danggui), Angelica acutiloba (Japanese Danggui), Angelica gigas (Korean Danggui) and Angelica archangelica L. (Europe Danggui). The results revealed that unambiguous differentiation could be achieved in each case, based on the mass patterns or principal component analysis of their respective MALDI spectra. Direct analysis of herbal powder or small pieces of raw samples by MALDI-MS, which avoids the extraction and/or homogenization procedures, was attempted and the acquired spectra also allowed differentiation of the herbal medicines. The approach developed in this study is simple, rapid, robust, and can be used for analysis of other herbal medicines. | en_US |
| dcterms.extent | xxi, 141 p. : ill. ; 30 cm. | en_US |
| dcterms.isPartOf | PolyU Electronic Theses | en_US |
| dcterms.issued | 2012 | en_US |
| dcterms.educationalLevel | All Master | en_US |
| dcterms.educationalLevel | M.Phil. | en_US |
| dcterms.LCSH | Herbs -- Analysis. | en_US |
| dcterms.LCSH | Materia medica, Vegetable -- Analysis. | en_US |
| dcterms.LCSH | Hong Kong Polytechnic University -- Dissertations | en_US |
| dcterms.accessRights | open access | en_US |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| b26158759.pdf | For All Users | 2.37 MB | Adobe PDF | View/Open |
Copyright Undertaking
As a bona fide Library user, I declare that:
- I will abide by the rules and legal ordinances governing copyright regarding the use of the Database.
- I will use the Database for the purpose of my research or private study only and not for circulation or further reproduction or any other purpose.
- I agree to indemnify and hold the University harmless from and against any loss, damage, cost, liability or expenses arising from copyright infringement or unauthorized usage.
By downloading any item(s) listed above, you acknowledge that you have read and understood the copyright undertaking as stated above, and agree to be bound by all of its terms.
Please use this identifier to cite or link to this item:
https://theses.lib.polyu.edu.hk/handle/200/6977